The clinical effect of homozygous ABCA4 alleles in 18 patients.

allelebio

OBJECTIVE
To illustrate the phenotypic presentation of a group of individuals with the homozygous variant ABCA4 related diseases.


METHOD
retrospective case series.

METHOD
Eighteen of the affected individuals from 13 families ascertained from the total cohort of 214 families with retinal diseases associated ABCA4 presenting to a single center.


METHOD
A detailed history was obtained, and color fundus photography, autofluorescence (AF) imaging, optical coherence tomography (OCT), and electrophysiologic assessment is done. Phenotype by ophthalmoscopy, AF, and electrophysiology are assigned using the characteristics previously reported. ABCA4 mutation detection is done using microarray ABCR400 (Asper Biotech, Tartu, Estonia) and high-throughput DNA sequencing, with direct sequencing used to assess segregation.


METHOD
Detailed clinical, electrophysiological and molecular genetic findings.


RESULTS
Eleven ABCA4 homozygous alleles related diseases were identified, including one shift frame, two stops, first intronic splice-site variants lead changes, two missense variants of the complex, and 5 of the missense variants: p.Glu905fsX916, p.Arg1300X, p.Gln2220X, c 0, 4253 + 4 C> T, p.Leu541Pro and p.Ala1038Val (homozygosity for allele complex), p.Val931Met and p.Arg1705Gln (complex alleles), p.Arg212Cys, p.Cys1488Arg, p.Arg1640Trp, p.Gly1961Glu, and p.Leu2027Phe. Eight of the 11 allele homozygotes have not been reported previously. Six of 7 patients with homozygous null allele had early-onset (<10 years) disease, with all seven had severe phenotype.

Two patients with homozygous missense variant (p.Leu541Pro and p.Ala1038Val [complex], and p.Arg1640Trp) served with a severe phenotype. Three patients with homozygous p.Gly1961Glu have adult-onset disease and mild phenotype. One patient with homozygous p.Leu2027Phe show fovea spared and preserved visual acuity.


CONCLUSION
Phenotype is represented in patients identified as homozygous for the variant considered ABCA4 related disease provides insight into the effects of individual alleles. Null alleles have functional effects are severe, and certain missense variant similar to nulls, suggesting a complete retraction of protein function. Common alleles were identified, p.Gly1961Glu and p. Leu2027Phe, both have structural and functional effects of light on the retina adults; the latter is associated with a relatively fixed photoreceptor architecture and function in the fovea.

 The clinical effect of homozygous ABCA4 alleles in 18 patients.
The clinical effect of homozygous ABCA4 alleles in 18 patients.

whole genome association studies for multigenic diseases: ethical dilemmas arising from commercialization – the case of genetic testing for autism.

This paper discusses some of the ethical issues that arise from whole genome association studies for multigenic diseases, with a focus on cases of autism. Events that occurred after the announcement of a genetic test for autism in France (2005-2009) described for example ethical controversy that can arise when a genetic test for autism is applied prematurely and inappropriately promoted by biotech companies.

p38 Antibody

48644-100ul 100ul
EUR 399.6

p38 Antibody

48644-50ul 50ul
EUR 286.8

p38 Antibody

35478-100ul 100ul
EUR 468

p38 Antibody

20-abx141038
  • EUR 427.20
  • EUR 644.40
  • EUR 260.40
  • 100 ul
  • 200 ul
  • 30 ul

p38 Antibody

20-abx133223
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

p38 Antibody

20-abx007541
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

p38 Antibody

abx236076-100ug 100 ug
EUR 577.2

p38 protein

E20-80078 20ug
EUR 489.6

p38 protein

E20-80079 20ug
EUR 489.6

anti-p38

YF-PA23519 50 ul
EUR 400.8
Description: Mouse polyclonal to p38

anti-p38

YF-PA23520 50 ul
EUR 400.8
Description: Mouse polyclonal to p38

anti-p38

YF-PA23521 50 ul
EUR 400.8
Description: Mouse polyclonal to p38

anti-p38

YF-PA11120 50 ug
EUR 435.6
Description: Mouse polyclonal to p38

anti-p38

YF-PA11121 100 ug
EUR 483.6
Description: Rabbit polyclonal to p38

PM 102

B5517-1 1 mg
EUR 721.2

MM-102

B1582-2 2 mg
EUR 153.6
Description: MM-102 is an antagonist of MLL1 with IC50 value of 2.4nM [1].Mixed lineage leukemia 1 (MLL1) is a histone H3 lysine 4 (H3K4) methyltransferase.

MM-102

B1582-20 20 mg
EUR 711.6
Description: MM-102 is an antagonist of MLL1 with IC50 value of 2.4nM [1].Mixed lineage leukemia 1 (MLL1) is a histone H3 lysine 4 (H3K4) methyltransferase.

PPQ-102

B3504-10 10 mg
EUR 290.4

PPQ-102

B3504-5 5 mg
EUR 181.2

PPQ-102

B3504-50 50 mg
EUR 1035.6

PPQ-102

HY-14179 100mg
EUR 1465.2

BGB-102

HY-15732 10mg
EUR 7249.2

EL-102

HY-16187 10mM/1mL
EUR 451.2

LSZ-102

HY-111486 50mg
EUR 3985.2

MM-102

HY-12220 10mg
EUR 357.6

IAXO-102

HY-125171 50mg
EUR 2332.8

MM-102

B2364-25 each
EUR 705.6

MM-102

B2364-5 each
EUR 222

5(6)-FAM [5-(and-6)-Carboxyfluorescein] *CAS 72088-94-9*

102 25 g
EUR 1051.2

SB-203580 p38 MAPK(p38 MAP kinase) Inhibitor

E1B1863 1mg
EUR 193.2

p38 MAPK antibody

10R-8422 100 ul
EUR 471.6
Description: Mouse monoclonal p38 MAPK antibody

P38 MAPK antibody

70R-34325 100 ug
EUR 392.4
Description: Rabbit polyclonal P38 MAPK antibody

P38 MAPK antibody

70R-34327 100 ug
EUR 392.4
Description: Rabbit polyclonal P38 MAPK antibody

p38 MAPK antibody

70R-33398 100 ug
EUR 392.4
Description: Rabbit polyclonal p38 MAPK antibody

p38 MAPK antibody

70R-33400 100 ug
EUR 392.4
Description: Rabbit polyclonal p38 MAPK antibody

P38 delta protein

30R-2868 5 ug
EUR 603.6
Description: Purified recombinant Human P38 delta protein

p38 alpha protein

30R-2870 5 ug
EUR 603.6
Description: Purified recombinant Human p38 alpha protein

p38 beta protein

30R-2875 5 ug
EUR 603.6
Description: Purified recombinant Human p38 beta protein

p38 Polyclonal Antibody

41305-100ul 100ul
EUR 302.4

p38 Polyclonal Antibody

41305-50ul 50ul
EUR 224.4

p38 Polyclonal Antibody

41306-100ul 100ul
EUR 302.4

p38 Polyclonal Antibody

41306-50ul 50ul
EUR 224.4

p38 MAPK Antibody

49379-100ul 100ul
EUR 399.6

p38 MAPK Antibody

49379-50ul 50ul
EUR 286.8

p38 MAPK antibody

20R-2950 100 ul
EUR 471.6
Description: Rabbit polyclonal p38 MAPK antibody

p38 MAPK antibody

20R-1572 100 ug
EUR 846
Description: Rabbit polyclonal p38 MAPK antibody

P38 MAPK antibody

20R-2087 50 ug
EUR 337.2
Description: Rabbit polyclonal P38 MAPK antibody

P38 MAPK antibody

20R-2088 50 ug
EUR 337.2
Description: Rabbit polyclonal P38 MAPK antibody

P38 MAPK antibody

20R-2403 50 ug
EUR 337.2
Description: Rabbit polyclonal P38 MAPK antibody

p38 (pY323) Antibody

20-abx133058
  • EUR 376.80
  • EUR 560.40
  • EUR 243.60
  • 100 ul
  • 200 ul
  • 30 ul

p38 (pY182) Antibody

20-abx134951
  • EUR 460.80
  • EUR 727.20
  • EUR 276.00
  • 100 ul
  • 200 ul
  • 30 ul

p38 Blocking Peptide

20-abx161932
  • EUR 326.40
  • EUR 493.20
  • 1 mg
  • 5 mg

p38 Polyclonal Antibody

ABP52112-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody

ABP52112-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody

ABP52112-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182

p38 Polyclonal Antibody

ABP52113-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Polyclonal Antibody

ABP52113-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Polyclonal Antibody

ABP52113-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323

p38 Polyclonal Antibody

ABP53838-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody

ABP53838-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody

ABP53838-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180

p38 Polyclonal Antibody

ABP53839-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 Polyclonal Antibody

ABP53839-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 Polyclonal Antibody

ABP53839-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182

p38 Polyclonal Antibody

ABP57354-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38

p38 Polyclonal Antibody

ABP57354-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38

p38 Polyclonal Antibody

ABP57354-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38

p38 Blocking Peptide

20-abx061736
  • EUR 309.60
  • EUR 460.80
  • 1 mg
  • 5 mg

p38 Blocking Peptide

20-abx062080
  • EUR 326.40
  • EUR 493.20
  • 1 mg
  • 5 mg

p38 (pT180) Antibody

20-abx009863
  • EUR 376.80
  • EUR 560.40
  • EUR 243.60
  • 100 ul
  • 200 ul
  • 30 ul

p38 MAPK Antibody

20-abx012798
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

p38 MAPK Antibody

20-abx012875
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

p38 MAPK Antibody

ABF6456 100 ug
EUR 525.6

p38 MAPK Antibody

abx236077-100ug 100 ug
EUR 577.2

Anti-p38 Antibody

A00176 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for p38 Antibody (MAPK14) detection.tested for WB in Human, Mouse, Rat.

Anti-p38 alpha

DB-1039 100 tests
EUR 568.8

Anti-p38 beta

DB-1040 100 tests
EUR 568.8

Anti-p38 gamma

DB-1041 100 tests
EUR 568.8

Anti-p38 delta

DB-1042 100 tests
EUR 568.8

Anti-p38-a

DB-161-0.05 50 μl
EUR 322.8

Anti-p38-a

DB-161-0.1 100 μl
EUR 506.4

Anti-p38-b

DB-162-0.05 50 μl
EUR 322.8

Anti-p38-b

DB-162-0.1 100 μl
EUR 506.4

Anti-p38-g

DB-163-0.05 50 μl
EUR 322.8

Anti-p38-g

DB-163-0.1 100 μl
EUR 506.4

Anti-p38-d

DB-164-0.05 50 μl
EUR 322.8

Anti-p38-d

DB-164-0.1 100 μl
EUR 506.4

Anti-p38 alpha

DB1039 100 tests
EUR 568.8

Anti-p38 beta

DB1040 100 tests
EUR 568.8

Anti-p38 gamma

DB1041 100 tests
EUR 568.8

Anti-p38 delta

DB1042 100 tests
EUR 568.8

AIMP2/p38 Antibody

DF12048 200ul
EUR 420

Crk p38 Antibody

AF6323 200ul
EUR 420

p38 MAPK Antibody

AF6455 200ul
EUR 420

p38 MAPK Antibody

AF6456 200ul
EUR 420

p38 MAPK Antibody

AF6457 200ul
EUR 420

p38 Polyclonal Antibody

ES3111-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p38 Polyclonal Antibody

ES3111-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p38 Polyclonal Antibody

ES3112-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

p38 Polyclonal Antibody

ES3112-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

p38 Polyclonal Antibody

ES4837-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

p38 Polyclonal Antibody

ES4837-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

p38 Polyclonal Antibody

ES4838-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

p38 Polyclonal Antibody

ES4838-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Anti-p38 antibody

PAab06076 100 ug
EUR 426

anti-p38 MAPK

LF-PA0160 100 ul
EUR 400.8
Description: Rabbit polyclonal to p38 MAPK

anti- p38 antibody

FNab06076 100µg
EUR 606.3
Description: Antibody raised against p38

p38 Polyclonal Antibody

ES8347-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat/Chicken. This antibody is tested and validated for WB, ELISA, WB, ELISA

p38 Polyclonal Antibody

ES8347-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat/Chicken. This antibody is tested and validated for WB, ELISA, WB, ELISA

Anti-p38 antibody

STJ94876 200 µl
EUR 236.4
Description: Rabbit polyclonal to p38.

Anti-p38 antibody

STJ94877 200 µl
EUR 236.4
Description: Rabbit polyclonal to p38.

Anti-p38 antibody

STJ94878 200 µl
EUR 236.4
Description: p38 is a protein encoded by the MAPK14 gene which is approximately 41,2 kDa. p38 is localised to the cytoplasm and nucleus. It is involved in activated TLR4 signalling, the IL-2 pathway, toll-like receptor signalling pathways, the VEGF signalling pathway and 4-1BB pathway. This protein falls under the MAP kinase family. It acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. p38 is expressed in the brain, heart, placenta, pancreas and skeletal muscle. Mutations in the MAPK14 gene may result in patellar tendinitis and lumbosacral lipoma. STJ94878 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of p38 protein.

Anti-p38 antibody

STJ94879 200 µl
EUR 236.4
Description: Rabbit polyclonal to p38.

Anti-P38 antibody

STJ98898 200 µl
EUR 236.4
Description: Mouse monoclonal to P38.

Anti-P38 antibody

STJ98899 200 µl
EUR 236.4
Description: Mouse monoclonal to P38.

Anti-p38 antibody

STJ97615 200 µl
EUR 236.4
Description: Rabbit polyclonal to p38.

anti-Crk p38

YF-PA23509 50 ul
EUR 400.8
Description: Mouse polyclonal to Crk p38

anti-Crk p38

YF-PA11088 50 ul
EUR 435.6
Description: Mouse polyclonal to Crk p38

anti-Crk p38

YF-PA11089 50 ug
EUR 435.6
Description: Mouse polyclonal to Crk p38

anti-Crk p38

YF-PA11090 100 ug
EUR 483.6
Description: Rabbit polyclonal to Crk p38

anti-AIMP2/p38

YF-PA15507 50 ug
EUR 435.6
Description: Mouse polyclonal to AIMP2/p38

p38 alpha-MAPK14

RA15053 100 ug
EUR 631.2

Anti-p38 (3D5)

YF-MA12551 200 ul
EUR 435.6
Description: Mouse monoclonal to p38

Anti-p38 (1C9)

YF-MA12552 100 ug
EUR 435.6
Description: Mouse monoclonal to p38

p38 MAPK Antibody

R20266-0.1ML 100ul
EUR 409

Crk Antibody p38

R31526 100 ug
EUR 419

p38 Antibody (MAPK14)

F50496-0.08ML 0.08 ml
EUR 165

p38 Antibody (MAPK14)

F50496-0.4ML 0.4 ml
EUR 379

p38 beta, Active

7763-100 each
EUR 5214

p38 beta, Active

7763-5 each
EUR 444

BP-1-102

HY-100493 100mg
EUR 1614

MM-102 (TFA)

HY-12220A 10mM/1mL
EUR 315.6

Mouse P38 Mitogen-activated Protein Kinase (MAPK P38) CLIA Kit

abx197397-96tests 96 tests
EUR 990

Mouse MAPK P38(P38 Mitogen-activated Protein Kinase) ELISA Kit

EM1199 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.75 ng/ml

p38 MAP Kinase antibody

70R-11620 100 ug
EUR 501.6
Description: Rabbit polyclonal p38 MAP Kinase antibody

Phospho-p38 MAPK antibody

70R-11824 100 ug
EUR 630
Description: Rabbit polyclonal Phospho-p38 MAPK antibody

p38 MAPK Rabbit pAb

A10832-100ul 100 ul
EUR 460.8

p38 MAPK Rabbit pAb

A10832-200ul 200 ul
EUR 664.8

p38 MAPK Rabbit pAb

A10832-20ul 20 ul
EUR 219.6

p38 MAPK Rabbit pAb

A10832-50ul 50 ul
EUR 318

p38 MAPK Rabbit pAb

A14401-100ul 100 ul
EUR 369.6

p38 MAPK Rabbit pAb

A14401-200ul 200 ul
EUR 550.8

p38 MAPK Rabbit pAb

A14401-20ul 20 ul
EUR 219.6

p38 MAPK Rabbit pAb

A14401-50ul 50 ul
EUR 267.6

p38 MAPK Rabbit pAb

A11340-100ul 100 ul
EUR 369.6

p38 MAPK Rabbit pAb

A11340-200ul 200 ul
EUR 550.8

p38 MAPK Rabbit pAb

A11340-20ul 20 ul
EUR 219.6

p38 MAPK Rabbit pAb

A11340-50ul 50 ul
EUR 267.6

p38 MAPK antibody (Thr180)

70R-37313 100 ug
EUR 418.8
Description: Rabbit Polyclonal p38 MAPK antibody (Thr180)

p38 MAPK antibody (Tyr182)

70R-37314 100 ug
EUR 418.8
Description: Rabbit Polyclonal p38 MAPK antibody (Tyr182)

P38 MAPK antibody (Thr179)

70R-34324 100 ug
EUR 392.4
Description: Rabbit polyclonal P38 MAPK antibody (Thr179)

P38 MAPK antibody (Tyr182)

70R-34326 100 ug
EUR 392.4
Description: Rabbit polyclonal P38 MAPK antibody (Tyr182)

p38 MAPK antibody (Tyr322)

70R-33397 100 ug
EUR 392.4
Description: Rabbit polyclonal p38 MAPK antibody (Tyr322)

p38 MAP Kinase antibody

20R-1458 100 ug
EUR 807.6
Description: Rabbit polyclonal p38 MAP Kinase antibody

p38 MAPK Monoclonal Antibody

27507-100ul 100ul
EUR 302.4

p38 MAPK Monoclonal Antibody

27507-50ul 50ul
EUR 224.4

p38 (pT180 / Y182) Antibody

20-abx133560
  • EUR 376.80
  • EUR 560.40
  • EUR 243.60
  • 100 ul
  • 200 ul
  • 30 ul

p38 (pY323) Blocking Peptide

20-abx161669
  • EUR 376.80
  • EUR 610.80
  • 1 mg
  • 5 mg

p38 MAPK Rabbit pAb

A5521-100ul 100 ul
EUR 369.6

p38 MAPK Rabbit pAb

A5521-200ul 200 ul
EUR 550.8

p38 MAPK Rabbit pAb

A5521-20ul 20 ul
EUR 219.6

p38 MAPK Rabbit pAb

A5521-50ul 50 ul
EUR 267.6

p38 (pY182) Blocking Peptide

20-abx061650
  • EUR 360.00
  • EUR 594.00
  • 1 mg
  • 5 mg

p38 (pT180) Blocking Peptide

20-abx062081
  • EUR 376.80
  • EUR 610.80
  • 1 mg
  • 5 mg

p38 MAPK Polyclonal Antibody

ABP59793-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of p38 MAPK from Human, Mouse, Rat. This p38 MAPK antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human p38 MAPK protein

p38 MAPK Polyclonal Antibody

ABP59793-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of p38 MAPK from Human, Mouse, Rat. This p38 MAPK antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human p38 MAPK protein

p38 MAPK Polyclonal Antibody

ABP59793-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of p38 MAPK from Human, Mouse, Rat. This p38 MAPK antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human p38 MAPK protein

p38 MAPK (pT180) Antibody

abx011783-100ug 100 ug
EUR 526.8

p38 MAPK (pY182) Antibody

20-abx011784
  • EUR 526.80
  • EUR 109.20
  • EUR 92.40
  • 100 ug
  • 10 ug
  • 5 ug

p38 MAPK (pY322) Antibody

20-abx011785
  • EUR 526.80
  • EUR 109.20
  • 100 ug
  • 10 ug

p38 MAPK Rabbit pAb

A8038-100ul 100 ul
EUR 369.6

p38 MAPK Rabbit pAb

A8038-200ul 200 ul
EUR 550.8

p38 MAPK Rabbit pAb

A8038-20ul 20 ul Ask for price

p38 MAPK Rabbit pAb

A8038-50ul 50 ul Ask for price

p38 MAPK Rabbit mAb

A4771 20 μL
EUR 18

Phospho p38 (Tyr323) Antibody

A1984-100 100 µl
EUR 454.8

Polyclonal MAPK14 / p38 Antibody

APR02822G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MAPK14 / p38 . This antibody is tested and proven to work in the following applications:

p38 MAPK Monoclonal Antibody

BF8015 100ul
EUR 420

p38 gamma/delta Antibody

DF10341 200ul
EUR 420

p38 MAPK Conjugated Antibody

C49379 100ul
EUR 476.4

p38 MAPK Blocking Peptide

AF6455-BP 1mg
EUR 234

p38 MAPK Blocking Peptide

AF6456-BP 1mg
EUR 234

p38 MAPK Blocking Peptide

AF6457-BP 1mg
EUR 234

p38 Polyclonal Conjugated Antibody

C41305 100ul
EUR 476.4

P38 (1G1) Monoclonal Antibody

EM1369-100ul 100ul
EUR 334.8
Description: A Mouse Monoclonal antibody against P38 (1G1) from Human/ Mouse/ Rat. This antibody is tested and validated for IHC

P38 (1G1) Monoclonal Antibody

EM1369-50ul 50ul
EUR 248.4
Description: A Mouse Monoclonal antibody against P38 (1G1) from Human/ Mouse/ Rat. This antibody is tested and validated for IHC

anti-p38 MAPK (6A1)

LF-MA0126 100 ul
EUR 400.8
Description: Mouse monoclonal to p38 MAPK

anti-p38 MAPK (3D5)

LF-MA10188 50 ug
EUR 435.6
Description: Mouse monoclonal to p38 MAPK

p38 MAPK Polyclonal Antibody

ES8901-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against p38 MAPK from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

p38 MAPK Polyclonal Antibody

ES8901-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against p38 MAPK from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

The authors suggest that the genetic tests assess one or several genes involved in the disorder multigenic only be useful if: (1) genetic association found in scientific studies to be statistically convincing, reproducible and also applies to populations of individuals deemed to belong (validity scientific); (2) The relative risk is given by the ‘high risk’ alleles should be high enough to be significant to the patient (significant impact); (3) the use of the test should lead to some improvement of outcomes for patients, the results of treatment adjusted if available, or at least from lifestyle adjustments (or destiny) requested by the new knowledge generated (clinical utility).

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