
OBJECTIVE
To illustrate the phenotypic presentation of a group of individuals with the homozygous variant ABCA4 related diseases.
METHOD
retrospective case series.
METHOD
Eighteen of the affected individuals from 13 families ascertained from the total cohort of 214 families with retinal diseases associated ABCA4 presenting to a single center.
METHOD
A detailed history was obtained, and color fundus photography, autofluorescence (AF) imaging, optical coherence tomography (OCT), and electrophysiologic assessment is done. Phenotype by ophthalmoscopy, AF, and electrophysiology are assigned using the characteristics previously reported. ABCA4 mutation detection is done using microarray ABCR400 (Asper Biotech, Tartu, Estonia) and high-throughput DNA sequencing, with direct sequencing used to assess segregation.
METHOD
Detailed clinical, electrophysiological and molecular genetic findings.
RESULTS
Eleven ABCA4 homozygous alleles related diseases were identified, including one shift frame, two stops, first intronic splice-site variants lead changes, two missense variants of the complex, and 5 of the missense variants: p.Glu905fsX916, p.Arg1300X, p.Gln2220X, c 0, 4253 + 4 C> T, p.Leu541Pro and p.Ala1038Val (homozygosity for allele complex), p.Val931Met and p.Arg1705Gln (complex alleles), p.Arg212Cys, p.Cys1488Arg, p.Arg1640Trp, p.Gly1961Glu, and p.Leu2027Phe. Eight of the 11 allele homozygotes have not been reported previously. Six of 7 patients with homozygous null allele had early-onset (<10 years) disease, with all seven had severe phenotype.
Two patients with homozygous missense variant (p.Leu541Pro and p.Ala1038Val [complex], and p.Arg1640Trp) served with a severe phenotype. Three patients with homozygous p.Gly1961Glu have adult-onset disease and mild phenotype. One patient with homozygous p.Leu2027Phe show fovea spared and preserved visual acuity.
CONCLUSION
Phenotype is represented in patients identified as homozygous for the variant considered ABCA4 related disease provides insight into the effects of individual alleles. Null alleles have functional effects are severe, and certain missense variant similar to nulls, suggesting a complete retraction of protein function. Common alleles were identified, p.Gly1961Glu and p. Leu2027Phe, both have structural and functional effects of light on the retina adults; the latter is associated with a relatively fixed photoreceptor architecture and function in the fovea.

whole genome association studies for multigenic diseases: ethical dilemmas arising from commercialization – the case of genetic testing for autism.
This paper discusses some of the ethical issues that arise from whole genome association studies for multigenic diseases, with a focus on cases of autism. Events that occurred after the announcement of a genetic test for autism in France (2005-2009) described for example ethical controversy that can arise when a genetic test for autism is applied prematurely and inappropriately promoted by biotech companies.
p38 Antibody |
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48644-100ul | SAB | 100ul | EUR 399.6 |
p38 Antibody |
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48644-50ul | SAB | 50ul | EUR 286.8 |
p38 Antibody |
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35478-100ul | SAB | 100ul | EUR 468 |
p38 Antibody |
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20-abx141038 | Abbexa |
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p38 Antibody |
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20-abx133223 | Abbexa |
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p38 Antibody |
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20-abx007541 | Abbexa |
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p38 Antibody |
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abx236076-100ug | Abbexa | 100 ug | EUR 577.2 |
p38 protein |
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E20-80078 | EnoGene | 20ug | EUR 489.6 |
p38 protein |
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E20-80079 | EnoGene | 20ug | EUR 489.6 |
anti-p38 |
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YF-PA23519 | Abfrontier | 50 ul | EUR 400.8 |
Description: Mouse polyclonal to p38 |
anti-p38 |
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YF-PA23520 | Abfrontier | 50 ul | EUR 400.8 |
Description: Mouse polyclonal to p38 |
anti-p38 |
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YF-PA23521 | Abfrontier | 50 ul | EUR 400.8 |
Description: Mouse polyclonal to p38 |
anti-p38 |
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YF-PA11120 | Abfrontier | 50 ug | EUR 435.6 |
Description: Mouse polyclonal to p38 |
anti-p38 |
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YF-PA11121 | Abfrontier | 100 ug | EUR 483.6 |
Description: Rabbit polyclonal to p38 |
PM 102 |
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B5517-1 | ApexBio | 1 mg | EUR 721.2 |
MM-102 |
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B1582-2 | ApexBio | 2 mg | EUR 153.6 |
Description: MM-102 is an antagonist of MLL1 with IC50 value of 2.4nM [1].Mixed lineage leukemia 1 (MLL1) is a histone H3 lysine 4 (H3K4) methyltransferase. |
MM-102 |
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B1582-20 | ApexBio | 20 mg | EUR 711.6 |
Description: MM-102 is an antagonist of MLL1 with IC50 value of 2.4nM [1].Mixed lineage leukemia 1 (MLL1) is a histone H3 lysine 4 (H3K4) methyltransferase. |
PPQ-102 |
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B3504-10 | ApexBio | 10 mg | EUR 290.4 |
PPQ-102 |
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B3504-5 | ApexBio | 5 mg | EUR 181.2 |
PPQ-102 |
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B3504-50 | ApexBio | 50 mg | EUR 1035.6 |
PPQ-102 |
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HY-14179 | MedChemExpress | 100mg | EUR 1465.2 |
BGB-102 |
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HY-15732 | MedChemExpress | 10mg | EUR 7249.2 |
EL-102 |
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HY-16187 | MedChemExpress | 10mM/1mL | EUR 451.2 |
LSZ-102 |
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HY-111486 | MedChemExpress | 50mg | EUR 3985.2 |
MM-102 |
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HY-12220 | MedChemExpress | 10mg | EUR 357.6 |
IAXO-102 |
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HY-125171 | MedChemExpress | 50mg | EUR 2332.8 |
MM-102 |
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B2364-25 | Biovision | each | EUR 705.6 |
MM-102 |
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B2364-5 | Biovision | each | EUR 222 |
5(6)-FAM [5-(and-6)-Carboxyfluorescein] *CAS 72088-94-9* |
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102 | AAT Bioquest | 25 g | EUR 1051.2 |
SB-203580 p38 MAPK(p38 MAP kinase) Inhibitor |
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E1B1863 | EnoGene | 1mg | EUR 193.2 |
p38 MAPK antibody |
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10R-8422 | Fitzgerald | 100 ul | EUR 471.6 |
Description: Mouse monoclonal p38 MAPK antibody |
P38 MAPK antibody |
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70R-34325 | Fitzgerald | 100 ug | EUR 392.4 |
Description: Rabbit polyclonal P38 MAPK antibody |
P38 MAPK antibody |
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70R-34327 | Fitzgerald | 100 ug | EUR 392.4 |
Description: Rabbit polyclonal P38 MAPK antibody |
p38 MAPK antibody |
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70R-33398 | Fitzgerald | 100 ug | EUR 392.4 |
Description: Rabbit polyclonal p38 MAPK antibody |
p38 MAPK antibody |
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70R-33400 | Fitzgerald | 100 ug | EUR 392.4 |
Description: Rabbit polyclonal p38 MAPK antibody |
P38 delta protein |
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30R-2868 | Fitzgerald | 5 ug | EUR 603.6 |
Description: Purified recombinant Human P38 delta protein |
p38 alpha protein |
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30R-2870 | Fitzgerald | 5 ug | EUR 603.6 |
Description: Purified recombinant Human p38 alpha protein |
p38 beta protein |
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30R-2875 | Fitzgerald | 5 ug | EUR 603.6 |
Description: Purified recombinant Human p38 beta protein |
p38 Polyclonal Antibody |
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41305-100ul | SAB | 100ul | EUR 302.4 |
p38 Polyclonal Antibody |
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41305-50ul | SAB | 50ul | EUR 224.4 |
p38 Polyclonal Antibody |
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41306-100ul | SAB | 100ul | EUR 302.4 |
p38 Polyclonal Antibody |
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41306-50ul | SAB | 50ul | EUR 224.4 |
p38 MAPK Antibody |
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49379-100ul | SAB | 100ul | EUR 399.6 |
p38 MAPK Antibody |
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49379-50ul | SAB | 50ul | EUR 286.8 |
p38 MAPK antibody |
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20R-2950 | Fitzgerald | 100 ul | EUR 471.6 |
Description: Rabbit polyclonal p38 MAPK antibody |
p38 MAPK antibody |
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20R-1572 | Fitzgerald | 100 ug | EUR 846 |
Description: Rabbit polyclonal p38 MAPK antibody |
P38 MAPK antibody |
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20R-2087 | Fitzgerald | 50 ug | EUR 337.2 |
Description: Rabbit polyclonal P38 MAPK antibody |
P38 MAPK antibody |
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20R-2088 | Fitzgerald | 50 ug | EUR 337.2 |
Description: Rabbit polyclonal P38 MAPK antibody |
P38 MAPK antibody |
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20R-2403 | Fitzgerald | 50 ug | EUR 337.2 |
Description: Rabbit polyclonal P38 MAPK antibody |
p38 (pY323) Antibody |
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20-abx133058 | Abbexa |
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p38 (pY182) Antibody |
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20-abx134951 | Abbexa |
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p38 Blocking Peptide |
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20-abx161932 | Abbexa |
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p38 Polyclonal Antibody |
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ABP52112-003ml | Abbkine | 0.03ml | EUR 189.6 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182 |
p38 Polyclonal Antibody |
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ABP52112-01ml | Abbkine | 0.1ml | EUR 346.8 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182 |
p38 Polyclonal Antibody |
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ABP52112-02ml | Abbkine | 0.2ml | EUR 496.8 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182 |
p38 Polyclonal Antibody |
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ABP52113-003ml | Abbkine | 0.03ml | EUR 189.6 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323 |
p38 Polyclonal Antibody |
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ABP52113-01ml | Abbkine | 0.1ml | EUR 346.8 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323 |
p38 Polyclonal Antibody |
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ABP52113-02ml | Abbkine | 0.2ml | EUR 496.8 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323 |
p38 Polyclonal Antibody |
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ABP53838-003ml | Abbkine | 0.03ml | EUR 189.6 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180 |
p38 Polyclonal Antibody |
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ABP53838-01ml | Abbkine | 0.1ml | EUR 346.8 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180 |
p38 Polyclonal Antibody |
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ABP53838-02ml | Abbkine | 0.2ml | EUR 496.8 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180 |
p38 Polyclonal Antibody |
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ABP53839-003ml | Abbkine | 0.03ml | EUR 189.6 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182 |
p38 Polyclonal Antibody |
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ABP53839-01ml | Abbkine | 0.1ml | EUR 346.8 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182 |
p38 Polyclonal Antibody |
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ABP53839-02ml | Abbkine | 0.2ml | EUR 496.8 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182 |
p38 Polyclonal Antibody |
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ABP57354-003ml | Abbkine | 0.03ml | EUR 189.6 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38 |
p38 Polyclonal Antibody |
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ABP57354-01ml | Abbkine | 0.1ml | EUR 346.8 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38 |
p38 Polyclonal Antibody |
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ABP57354-02ml | Abbkine | 0.2ml | EUR 496.8 |
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38 |
p38 Blocking Peptide |
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20-abx061736 | Abbexa |
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p38 Blocking Peptide |
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20-abx062080 | Abbexa |
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p38 (pT180) Antibody |
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20-abx009863 | Abbexa |
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p38 MAPK Antibody |
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20-abx012798 | Abbexa |
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p38 MAPK Antibody |
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20-abx012875 | Abbexa |
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p38 MAPK Antibody |
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ABF6456 | Lifescience Market | 100 ug | EUR 525.6 |
p38 MAPK Antibody |
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abx236077-100ug | Abbexa | 100 ug | EUR 577.2 |
Anti-p38 Antibody |
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A00176 | BosterBio | 100ul | EUR 476.4 |
Description: Rabbit Polyclonal Antibody for p38 Antibody (MAPK14) detection.tested for WB in Human, Mouse, Rat. |
Anti-p38 alpha |
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DB-1039 | DB Biotech | 100 tests | EUR 568.8 |
Anti-p38 beta |
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DB-1040 | DB Biotech | 100 tests | EUR 568.8 |
Anti-p38 gamma |
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DB-1041 | DB Biotech | 100 tests | EUR 568.8 |
Anti-p38 delta |
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DB-1042 | DB Biotech | 100 tests | EUR 568.8 |
Anti-p38-a |
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DB-161-0.05 | DB Biotech | 50 μl | EUR 322.8 |
Anti-p38-a |
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DB-161-0.1 | DB Biotech | 100 μl | EUR 506.4 |
Anti-p38-b |
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DB-162-0.05 | DB Biotech | 50 μl | EUR 322.8 |
Anti-p38-b |
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DB-162-0.1 | DB Biotech | 100 μl | EUR 506.4 |
Anti-p38-g |
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DB-163-0.05 | DB Biotech | 50 μl | EUR 322.8 |
Anti-p38-g |
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DB-163-0.1 | DB Biotech | 100 μl | EUR 506.4 |
Anti-p38-d |
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DB-164-0.05 | DB Biotech | 50 μl | EUR 322.8 |
Anti-p38-d |
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DB-164-0.1 | DB Biotech | 100 μl | EUR 506.4 |
Anti-p38 alpha |
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DB1039 | DB Biotech | 100 tests | EUR 568.8 |
Anti-p38 beta |
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DB1040 | DB Biotech | 100 tests | EUR 568.8 |
Anti-p38 gamma |
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DB1041 | DB Biotech | 100 tests | EUR 568.8 |
Anti-p38 delta |
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DB1042 | DB Biotech | 100 tests | EUR 568.8 |
AIMP2/p38 Antibody |
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DF12048 | Affbiotech | 200ul | EUR 420 |
Crk p38 Antibody |
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AF6323 | Affbiotech | 200ul | EUR 420 |
p38 MAPK Antibody |
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AF6455 | Affbiotech | 200ul | EUR 420 |
p38 MAPK Antibody |
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AF6456 | Affbiotech | 200ul | EUR 420 |
p38 MAPK Antibody |
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AF6457 | Affbiotech | 200ul | EUR 420 |
p38 Polyclonal Antibody |
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ES3111-100ul | ELK Biotech | 100ul | EUR 334.8 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
p38 Polyclonal Antibody |
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ES3111-50ul | ELK Biotech | 50ul | EUR 248.4 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
p38 Polyclonal Antibody |
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ES3112-100ul | ELK Biotech | 100ul | EUR 334.8 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
p38 Polyclonal Antibody |
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ES3112-50ul | ELK Biotech | 50ul | EUR 248.4 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
p38 Polyclonal Antibody |
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ES4837-100ul | ELK Biotech | 100ul | EUR 334.8 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
p38 Polyclonal Antibody |
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ES4837-50ul | ELK Biotech | 50ul | EUR 248.4 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
p38 Polyclonal Antibody |
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ES4838-100ul | ELK Biotech | 100ul | EUR 334.8 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
p38 Polyclonal Antibody |
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ES4838-50ul | ELK Biotech | 50ul | EUR 248.4 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
Anti-p38 antibody |
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PAab06076 | Lifescience Market | 100 ug | EUR 426 |
anti-p38 MAPK |
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LF-PA0160 | Abfrontier | 100 ul | EUR 400.8 |
Description: Rabbit polyclonal to p38 MAPK |
anti- p38 antibody |
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FNab06076 | FN Test | 100µg | EUR 606.3 |
Description: Antibody raised against p38 |
p38 Polyclonal Antibody |
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ES8347-100ul | ELK Biotech | 100ul | EUR 334.8 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat/Chicken. This antibody is tested and validated for WB, ELISA, WB, ELISA |
p38 Polyclonal Antibody |
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ES8347-50ul | ELK Biotech | 50ul | EUR 248.4 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat/Chicken. This antibody is tested and validated for WB, ELISA, WB, ELISA |
Anti-p38 antibody |
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STJ94876 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to p38. |
Anti-p38 antibody |
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STJ94877 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to p38. |
Anti-p38 antibody |
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STJ94878 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: p38 is a protein encoded by the MAPK14 gene which is approximately 41,2 kDa. p38 is localised to the cytoplasm and nucleus. It is involved in activated TLR4 signalling, the IL-2 pathway, toll-like receptor signalling pathways, the VEGF signalling pathway and 4-1BB pathway. This protein falls under the MAP kinase family. It acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. p38 is expressed in the brain, heart, placenta, pancreas and skeletal muscle. Mutations in the MAPK14 gene may result in patellar tendinitis and lumbosacral lipoma. STJ94878 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of p38 protein. |
Anti-p38 antibody |
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STJ94879 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to p38. |
Anti-P38 antibody |
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STJ98898 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Mouse monoclonal to P38. |
Anti-P38 antibody |
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STJ98899 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Mouse monoclonal to P38. |
Anti-p38 antibody |
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STJ97615 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Rabbit polyclonal to p38. |
anti-Crk p38 |
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YF-PA23509 | Abfrontier | 50 ul | EUR 400.8 |
Description: Mouse polyclonal to Crk p38 |
anti-Crk p38 |
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YF-PA11088 | Abfrontier | 50 ul | EUR 435.6 |
Description: Mouse polyclonal to Crk p38 |
anti-Crk p38 |
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YF-PA11089 | Abfrontier | 50 ug | EUR 435.6 |
Description: Mouse polyclonal to Crk p38 |
anti-Crk p38 |
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YF-PA11090 | Abfrontier | 100 ug | EUR 483.6 |
Description: Rabbit polyclonal to Crk p38 |
anti-AIMP2/p38 |
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YF-PA15507 | Abfrontier | 50 ug | EUR 435.6 |
Description: Mouse polyclonal to AIMP2/p38 |
p38 alpha-MAPK14 |
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RA15053 | Neuromics | 100 ug | EUR 631.2 |
Anti-p38 (3D5) |
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YF-MA12551 | Abfrontier | 200 ul | EUR 435.6 |
Description: Mouse monoclonal to p38 |
Anti-p38 (1C9) |
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YF-MA12552 | Abfrontier | 100 ug | EUR 435.6 |
Description: Mouse monoclonal to p38 |
p38 MAPK Antibody |
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R20266-0.1ML | NSJ Bioreagents | 100ul | EUR 409 |
Crk Antibody p38 |
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R31526 | NSJ Bioreagents | 100 ug | EUR 419 |
p38 Antibody (MAPK14) |
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F50496-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 165 |
p38 Antibody (MAPK14) |
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F50496-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 379 |
p38 beta, Active |
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7763-100 | Biovision | each | EUR 5214 |
p38 beta, Active |
|||
7763-5 | Biovision | each | EUR 444 |
BP-1-102 |
|||
HY-100493 | MedChemExpress | 100mg | EUR 1614 |
MM-102 (TFA) |
|||
HY-12220A | MedChemExpress | 10mM/1mL | EUR 315.6 |
Mouse P38 Mitogen-activated Protein Kinase (MAPK P38) CLIA Kit |
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abx197397-96tests | Abbexa | 96 tests | EUR 990 |
Mouse MAPK P38(P38 Mitogen-activated Protein Kinase) ELISA Kit |
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EM1199 | FN Test | 96T | EUR 628.92 |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.75 ng/ml |
p38 MAP Kinase antibody |
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70R-11620 | Fitzgerald | 100 ug | EUR 501.6 |
Description: Rabbit polyclonal p38 MAP Kinase antibody |
Phospho-p38 MAPK antibody |
|||
70R-11824 | Fitzgerald | 100 ug | EUR 630 |
Description: Rabbit polyclonal Phospho-p38 MAPK antibody |
p38 MAPK Rabbit pAb |
|||
A10832-100ul | Abclonal | 100 ul | EUR 460.8 |
p38 MAPK Rabbit pAb |
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A10832-200ul | Abclonal | 200 ul | EUR 664.8 |
p38 MAPK Rabbit pAb |
|||
A10832-20ul | Abclonal | 20 ul | EUR 219.6 |
p38 MAPK Rabbit pAb |
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A10832-50ul | Abclonal | 50 ul | EUR 318 |
p38 MAPK Rabbit pAb |
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A14401-100ul | Abclonal | 100 ul | EUR 369.6 |
p38 MAPK Rabbit pAb |
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A14401-200ul | Abclonal | 200 ul | EUR 550.8 |
p38 MAPK Rabbit pAb |
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A14401-20ul | Abclonal | 20 ul | EUR 219.6 |
p38 MAPK Rabbit pAb |
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A14401-50ul | Abclonal | 50 ul | EUR 267.6 |
p38 MAPK Rabbit pAb |
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A11340-100ul | Abclonal | 100 ul | EUR 369.6 |
p38 MAPK Rabbit pAb |
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A11340-200ul | Abclonal | 200 ul | EUR 550.8 |
p38 MAPK Rabbit pAb |
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A11340-20ul | Abclonal | 20 ul | EUR 219.6 |
p38 MAPK Rabbit pAb |
|||
A11340-50ul | Abclonal | 50 ul | EUR 267.6 |
p38 MAPK antibody (Thr180) |
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70R-37313 | Fitzgerald | 100 ug | EUR 418.8 |
Description: Rabbit Polyclonal p38 MAPK antibody (Thr180) |
p38 MAPK antibody (Tyr182) |
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70R-37314 | Fitzgerald | 100 ug | EUR 418.8 |
Description: Rabbit Polyclonal p38 MAPK antibody (Tyr182) |
P38 MAPK antibody (Thr179) |
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70R-34324 | Fitzgerald | 100 ug | EUR 392.4 |
Description: Rabbit polyclonal P38 MAPK antibody (Thr179) |
P38 MAPK antibody (Tyr182) |
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70R-34326 | Fitzgerald | 100 ug | EUR 392.4 |
Description: Rabbit polyclonal P38 MAPK antibody (Tyr182) |
p38 MAPK antibody (Tyr322) |
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70R-33397 | Fitzgerald | 100 ug | EUR 392.4 |
Description: Rabbit polyclonal p38 MAPK antibody (Tyr322) |
p38 MAP Kinase antibody |
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20R-1458 | Fitzgerald | 100 ug | EUR 807.6 |
Description: Rabbit polyclonal p38 MAP Kinase antibody |
p38 MAPK Monoclonal Antibody |
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27507-100ul | SAB | 100ul | EUR 302.4 |
p38 MAPK Monoclonal Antibody |
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27507-50ul | SAB | 50ul | EUR 224.4 |
p38 (pT180 / Y182) Antibody |
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20-abx133560 | Abbexa |
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p38 (pY323) Blocking Peptide |
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20-abx161669 | Abbexa |
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p38 MAPK Rabbit pAb |
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A5521-100ul | Abclonal | 100 ul | EUR 369.6 |
p38 MAPK Rabbit pAb |
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A5521-200ul | Abclonal | 200 ul | EUR 550.8 |
p38 MAPK Rabbit pAb |
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A5521-20ul | Abclonal | 20 ul | EUR 219.6 |
p38 MAPK Rabbit pAb |
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A5521-50ul | Abclonal | 50 ul | EUR 267.6 |
p38 (pY182) Blocking Peptide |
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20-abx061650 | Abbexa |
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p38 (pT180) Blocking Peptide |
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20-abx062081 | Abbexa |
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p38 MAPK Polyclonal Antibody |
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ABP59793-003ml | Abbkine | 0.03ml | EUR 189.6 |
Description: A polyclonal antibody for detection of p38 MAPK from Human, Mouse, Rat. This p38 MAPK antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human p38 MAPK protein |
p38 MAPK Polyclonal Antibody |
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ABP59793-01ml | Abbkine | 0.1ml | EUR 346.8 |
Description: A polyclonal antibody for detection of p38 MAPK from Human, Mouse, Rat. This p38 MAPK antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human p38 MAPK protein |
p38 MAPK Polyclonal Antibody |
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ABP59793-02ml | Abbkine | 0.2ml | EUR 496.8 |
Description: A polyclonal antibody for detection of p38 MAPK from Human, Mouse, Rat. This p38 MAPK antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human p38 MAPK protein |
p38 MAPK (pT180) Antibody |
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abx011783-100ug | Abbexa | 100 ug | EUR 526.8 |
p38 MAPK (pY182) Antibody |
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20-abx011784 | Abbexa |
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p38 MAPK (pY322) Antibody |
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20-abx011785 | Abbexa |
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p38 MAPK Rabbit pAb |
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A8038-100ul | Abclonal | 100 ul | EUR 369.6 |
p38 MAPK Rabbit pAb |
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A8038-200ul | Abclonal | 200 ul | EUR 550.8 |
p38 MAPK Rabbit pAb |
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A8038-20ul | Abclonal | 20 ul | Ask for price |
p38 MAPK Rabbit pAb |
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A8038-50ul | Abclonal | 50 ul | Ask for price |
p38 MAPK Rabbit mAb |
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A4771 | Abclonal | 20 μL | EUR 18 |
Phospho p38 (Tyr323) Antibody |
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A1984-100 | Biovision | 100 µl | EUR 454.8 |
Polyclonal MAPK14 / p38 Antibody |
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APR02822G | Leading Biology | 0.05ml | EUR 580.8 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MAPK14 / p38 . This antibody is tested and proven to work in the following applications: |
p38 MAPK Monoclonal Antibody |
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BF8015 | Affbiotech | 100ul | EUR 420 |
p38 gamma/delta Antibody |
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DF10341 | Affbiotech | 200ul | EUR 420 |
p38 MAPK Conjugated Antibody |
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C49379 | SAB | 100ul | EUR 476.4 |
p38 MAPK Blocking Peptide |
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AF6455-BP | Affbiotech | 1mg | EUR 234 |
p38 MAPK Blocking Peptide |
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AF6456-BP | Affbiotech | 1mg | EUR 234 |
p38 MAPK Blocking Peptide |
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AF6457-BP | Affbiotech | 1mg | EUR 234 |
p38 Polyclonal Conjugated Antibody |
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C41305 | SAB | 100ul | EUR 476.4 |
P38 (1G1) Monoclonal Antibody |
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EM1369-100ul | ELK Biotech | 100ul | EUR 334.8 |
Description: A Mouse Monoclonal antibody against P38 (1G1) from Human/ Mouse/ Rat. This antibody is tested and validated for IHC |
P38 (1G1) Monoclonal Antibody |
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EM1369-50ul | ELK Biotech | 50ul | EUR 248.4 |
Description: A Mouse Monoclonal antibody against P38 (1G1) from Human/ Mouse/ Rat. This antibody is tested and validated for IHC |
anti-p38 MAPK (6A1) |
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LF-MA0126 | Abfrontier | 100 ul | EUR 400.8 |
Description: Mouse monoclonal to p38 MAPK |
anti-p38 MAPK (3D5) |
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LF-MA10188 | Abfrontier | 50 ug | EUR 435.6 |
Description: Mouse monoclonal to p38 MAPK |
p38 MAPK Polyclonal Antibody |
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ES8901-100ul | ELK Biotech | 100ul | EUR 334.8 |
Description: A Rabbit Polyclonal antibody against p38 MAPK from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA |
p38 MAPK Polyclonal Antibody |
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ES8901-50ul | ELK Biotech | 50ul | EUR 248.4 |
Description: A Rabbit Polyclonal antibody against p38 MAPK from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA |
The authors suggest that the genetic tests assess one or several genes involved in the disorder multigenic only be useful if: (1) genetic association found in scientific studies to be statistically convincing, reproducible and also applies to populations of individuals deemed to belong (validity scientific); (2) The relative risk is given by the ‘high risk’ alleles should be high enough to be significant to the patient (significant impact); (3) the use of the test should lead to some improvement of outcomes for patients, the results of treatment adjusted if available, or at least from lifestyle adjustments (or destiny) requested by the new knowledge generated (clinical utility).